St. Macrina the Younger has a fascinating fourth-century discourse on science and technology. Macrina, who lived from 330 to 379 A.D., was the sister of St. Basil the Great and St. Gregory of Nyssa, and the daughter of St. Emmelia, and the granddaughter of St. Macrina the Elder (saints run thick in that family). Her discourse on science and technology was recorded by St. Gregory: it was part of their dialogue that became Gregory’s On the Soul and the Resurrection.
Macrina discusses how we know more than just what our eyes show us, because through our minds we take what our eyes see and we reason and we calculate; and we come to know, for example, that the sun is far larger than the Earth (science), and how to create machinery that can even imitate human actions (technology). Check out what St. Macrina the Younger has to say—her discourse is available on the Vatican Observatory Faith and Science pages: